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Search Results for " chronic obstructive pulmonary disease "

20

Compounds

Cat No. Product Name Synonyms Targets
T1532 Pidotimod Others , Antibacterial
Pidotimod is a synthetic dipeptide with immunomodulatory properties.
T6054 GSK256066 PDE
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
TN1355 Acanthoside B Immunology/Inflammation related
Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.
T30258 AZD-4818 CCR1 antagonist CCR
AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.
T4503 Talniflumate Somalgen Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o...
T1083 Theophylline Theo-24,1,3-Dimethylxanthine Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T6445 Cilomilast SB-207499,Ariflo PDE
Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.
T6547 Ipratropium Bromide Sch 1000,Itrop,Atrovent AChR
Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.
T26795 PXS-4728A BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl Monoamine Oxidase
BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].
T0098 Ipratropium bromide monohydrate Ipratropium bromide hydrate AChR
Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial...
T1083L Theophylline monohydrate Quibron HDAC , PDE , Adenosine Receptor
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...
T34387 Ronomilast ELB353,ELB 353,ELB-353,Elbimilast
Ronomilast(Elbimilast, ELB 353) is a PDE4 inhibitor for chronic inflammatory disease. Ronomilast is developed to treat chronic obstructive pulmonary disease (COPD).
T33386 Milveterol HCl Milveterol,GSK-159797,GSK 159797,GSK159797 Adrenergic Receptor
Milveterol HCl is a long-acting β(2) -adrenergic receptor agonist for the potential treatment of chronic obstructive pulmonary disease (COPD).
T26760 Bedoradrine sulfate KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246 Adrenergic Receptor
Bedoradrine sulfate (MN-221 sulfate) is a super-selective beta2 agonist for the treatment of asthma exacerbations and chronic obstructive pulmonary disease.
T30232 AWD 12-281 GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470 PDE
AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory and bronchodilator activity used in the study of chronic obstructive pulmonary disease (COPD).
T12850 Dilmapimod SB-681323,GW 681323 p38 MAPK , Autophagy
Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
T9877 Tiquizium AChR
Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.
T83168 Aderamastat FP-025 MMP
Aderamastat (FP-025) is an orally active inhibitor of matrix metalloproteinase 12 (MMP-12), utilized in the research of conditions such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis [1].
T6505 Formoterol fumarate Formoterol Hemifumarate,NSC 299587,Eformoterol Hemifumarate,CGP 25827A,Eformoterol,YM 08316 Adrenergic Receptor
Formoterol fumarate (Eformoterol Hemifumarate), an effective, specific and long-acting β2-adrenoceptor agonist, is utilized in the treatment of chronic obstructive pulmonary disease(COPD) and asthma.
T31207 GSK233705 Darotropium bromide,GSK 233705,GSK-233705B,GSK233705,GSK233705B,GSK-233705,GSK 233705B AChR
GSK233705 (Darotropium bromide) is a muscarinic receptor antagonist used in conjunction with the prevention and treatment of chronic obstructive pulmonary disease (COPD) and asthma in humans.

Compounds

Pidotimod
T1532
Synonym:
Target: Others, Antibacterial
GSK256066
T6054
Synonym:
Target: PDE
Acanthoside B
TN1355
Synonym:
Target: Immunology/Inflammation related
AZD-4818
T30258
Synonym: CCR1 antagonist
Target: CCR
Talniflumate
T4503
Synonym: Somalgen
Target: Chloride channel, COX, N-Acetylglucosaminyltransferase, Anion Exchanger
Theophylline
T1083
Synonym: Theo-24,1,3-Dimethylxanthine
Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy
Cilomilast
T6445
Synonym: SB-207499,Ariflo
Target: PDE
Ipratropium Bromide
T6547
Synonym: Sch 1000,Itrop,Atrovent
Target: AChR
PXS-4728A
T26795
Synonym: BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl
Target: Monoamine Oxidase
Ipratropium bromide monohydrate
T0098
Synonym: Ipratropium bromide hydrate
Target: AChR
Theophylline monohydrate
T1083L
Synonym: Quibron
Target: HDAC, PDE, Adenosine Receptor
Ronomilast
T34387
Synonym: ELB353,ELB 353,ELB-353,Elbimilast
Target:
Milveterol HCl
T33386
Synonym: Milveterol,GSK-159797,GSK 159797,GSK159797
Target: Adrenergic Receptor
Bedoradrine sulfate
T26760
Synonym: KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246
Target: Adrenergic Receptor
AWD 12-281
T30232
Synonym: GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470
Target: PDE
Dilmapimod
T12850
Synonym: SB-681323,GW 681323
Target: p38 MAPK, Autophagy
Tiquizium
T9877
Synonym:
Target: AChR
Aderamastat
T83168
Synonym: FP-025
Target: MMP
Formoterol fumarate
T6505
Synonym: Formoterol Hemifumarate,NSC 299587,Eformoterol Hemifumarate,CGP 25827A,Eformoterol,YM 08316
Target: Adrenergic Receptor
GSK233705
T31207
Synonym: Darotropium bromide,GSK 233705,GSK-233705B,GSK233705,GSK233705B,GSK-233705,GSK 233705B
Target: AChR
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TargetMol